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Intrauterine hyperglycemia impairs memory across two generations

20 Aug 2021

Abstract excerpt

Studies on humans and animals suggest associations between gestational diabetes mellitus (GDM) with increased susceptibility to develop neurological disorders in offspring. However, the molecular mechanisms underpinning the intergenerational effects remain unclear. Using a mouse model of diabetes during pregnancy, we found that intrauterine hyperglycemia exposure resulted in memory impairment in both the first...

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PMID: 34417446
DOI: 10.1038/s41398-021-01565-7

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