Article
Novel Immune Cell-Based Therapies to Eradicate High-Risk Acute Myeloid Leukemia.
Frontiers in immunology - 1 Jan 2021
Limongello Roberto, Marra Andrea, Mancusi Antonella, Bonato Samanta, Hoxha Eni, Ruggeri Loredana, Hui Susanta, Velardi Andrea, Pierini Antonio
Abstract excerpt
Adverse genetic risk acute myeloid leukemia (AML) includes a wide range of clinical-pathological entities with extremely poor outcomes; thus, novel therapeutic approaches are needed. Promising results achieved by engineered chimeric antigen receptor (CAR) T cells in other blood neoplasms have paved the way for the development of immune cell-based therapies for adverse genetic risk AML. Among these, adoptive cell...
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