Article
Predicting prognosis and IDH mutation status for patients with lower-grade gliomas using whole slide images.
Scientific reports - 19 Aug 2021
Jiang Shuai, Zanazzi George J, Hassanpour Saeed
Abstract excerpt
We developed end-to-end deep learning models using whole slide images of adults diagnosed with diffusely infiltrating, World Health Organization (WHO) grade 2 gliomas to predict prognosis and the mutation status of a somatic biomarker, isocitrate dehydrogenase (IDH) 1/2. The models, which utilize ResNet-18 as a backbone, were developed and validated on 296 patients from The Cancer Genome Atlas (TCGA) database. To...
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