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Article

Isocitrate dehydrogenase (IDH) status prediction in histopathology images of gliomas using deep learning.

Scientific reports - 7 May 2020

Liu Sidong, Shah Zubair, Sav Aydin, Russo Carlo, Berkovsky Shlomo, Qian Yi, Coiera Enrico, Di Ieva Antonio

Abstract excerpt

Mutations in isocitrate dehydrogenase genes IDH1 and IDH2 are frequently found in diffuse and anaplastic astrocytic and oligodendroglial tumours as well as in secondary glioblastomas. As IDH is a very important prognostic, diagnostic and therapeutic biomarker for glioma, it is of paramount importance to determine its mutational status. The haematoxylin and eosin (H&E) staining is a valuable tool in precision...

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Identifiers

PMID: 32382048
DOI: 10.1038/s41598-020-64588-y
PMCID: PMC7206037

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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