Article
Computational Pathology for Prediction of Isocitrate Dehydrogenase Gene Mutation from Whole Slide Images in Adult Patients with Diffuse Glioma.
The American journal of pathology - 1 May 2024
Zhao Yuanshen, Wang Weiwei, Ji Yuchen, Guo Yang, Duan Jingxian, Liu Xianzhi, Yan Dongming, Liang Dong, Li Wencai, Zhang Zhenyu, Li Zhi-Cheng
Abstract excerpt
Isocitrate dehydrogenase gene (IDH) mutation is one of the most important molecular markers of glioma. Accurate detection of IDH status is a crucial step for integrated diagnosis of adult-type diffuse gliomas. Herein, a clustering-based hybrid of a convolutional neural network and a vision transformer deep learning model was developed to detect IDH mutation status from annotation-free hematoxylin and...
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