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Age and gender differences in ACE2 and TMPRSS2 expressions in oral epithelial cells

19 Aug 2021

Abstract excerpt

BACKGROUND: SARS-CoV-2, which has brought a huge negative impact on the world since the end of 2019, is reported to invade cells using the spike (S) protein to bind to angiotensin-converting enzyme II (ACE2) receptors on human cells while the transmembrane protease serine 2 (TMPRSS2) is the key protease that activates the S protein, which greatly facilitates the entry of SARS-CoV-2 into target cells. In our...

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PMID: 34412632
DOI: 10.1186/s12967-021-03037-4

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