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Article

Influence of fibroids on cell‐free DNA screening accuracy

16 Aug 2021

Abstract excerpt

OBJECTIVE: Cell-free DNA (cfDNA) screening assesses both maternal and placental cfDNA. Fibroids are common and release cfDNA into maternal serum. Genetic abnormality is seen in 50% of fibroids. We aimed to assess the impact of fibroids on the accuracy of genome-wide cfDNA screening. METHODS: This was a prospective cohort study of singleton pregnancies examined at one of two centers in Melbourne and Sydney,...

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PMID: 34396623
DOI: 10.1002/uog.23763

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