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Prenatal cfDNA Sequencing and Incidental Detection of Maternal Cancer

4 Dec 2024

Abstract excerpt

BACKGROUND: Cell-free DNA (cfDNA) sequence analysis to screen for fetal aneuploidy can incidentally detect maternal cancer. Additional data are needed to identify DNA-sequencing patterns and other biomarkers that can identify pregnant persons who are most likely to have cancer and to determine the best approach for follow-up. METHODS: In this ongoing study we performed cancer screening in pregnant or postpartum...

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PMID: 39774314
DOI: 10.1056/nejmoa2401029

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