Article
Investigating the outcomes of pregnancies with atypical results following SNP-based cfDNA screening: a population-based cohort study.
American journal of obstetrics & gynecology MFM - 1 Oct 2026
Bellai-Dussault Kara, Dougan Shelley D, Okun Nan, Hull Danna, Lazzaro Sandra, Goh Elaine Suk-Ying, Siciliano Dawn, Gardiner Kate, Carter Ronald, Armour Christine M
Abstract excerpt
BACKGROUND: Cell-free DNA (cfDNA) screening has transformed prenatal screening by offering superior performance for detecting common aneuploidies, though it occasionally yields nonreportable or uninterpretable results. In 2020, a SNP-based cfDNA platform introduced a new category of nonreportable results termed "atypical," indicating additional or unexpected findings during DNA analysis. The clinical significance...
Read the complete abstract on PubMedTopics
- Humans
- Female
- Pregnancy
- Pregnancy Outcome
- Adult
- Cell-Free Nucleic Acids