Article
Comparisons of oxygen gradient ektacytometry parameters between sickle cell patients with or without α-thalassaemia.
British journal of haematology - 1 Nov 2021
Boisson Camille, Renoux Céline, Nader Elie, Gauthier Alexandra, Poutrel Solène, Rab Minke, Fort Romain, Bertrand Yves, Stauffer Emeric, Cannas Giovanna, Kebaili Kamila, Virot Emilie, Hot Arnaud, Sheehan Vivien, van Beers Eduard, van Wijk Richard, Joly Philippe, Connes Philippe
Abstract excerpt
The present study tested the impact of α-thalassaemia on oxygen gradient ektacytometry in sickle cell anaemia (SCA). Three SCA groups were compared: (i) no α-thalassaemia (four α-genes, n = 62), (ii) silent α-thalassaemia (three α-genes, n = 35) and (iii) homozygous α-thalassaemia (two α-genes, n = 12). Red blood cell (RBC) deformability measured in normoxia was not different between the three groups. The lowest...
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