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Article

Complement in Lupus: Biomarker, Therapeutic Target, or a Little Bit of Both?

26 Jun 2021

Abstract excerpt

Systemic lupus erythematosus (SLE) is an autoimmune disease with complex pathogenesis involving genetic, hormonal, and environmental factors.1 Mechanistically, evidence shows that dysfunctional apoptotic cell clearance and intracellular autoantigen exposure, together with abnormalities in lymphocyte signaling and interferon production pathways, are key drivers leading to formation of autoantibodies and pathogenic...

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PMID: 34386652
DOI: 10.1016/j.ekir.2021.06.016

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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