Context-Dependent Roles of Claudins in Tumorigenesis

Abstract excerpt

The barrier and fence functions of the claudin protein family are fundamental to tissue integrity and human health. Increasing evidence has linked claudins to signal transduction and tumorigenesis. The expression of claudins is frequently dysregulated in the context of neoplastic transformation. Studies have uncovered that claudins engage in nearly all aspects of tumor biology and steps of tumor development,...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Barrier Structure and Function Studies
• Share to Ferroptosis and cancer prognosis
• Share to Neurological Disease Mechanisms and Treatments