Article
Cross-species pathogenicity of gyrovirus 3 in experimentally infected chickens and mice.
Veterinary microbiology - 1 Oct 2021
Yuan Shiyu, Yan Tianxing, Huang Libo, Hao Xiaojing, Zhao Manda, Zhang Shicheng, Zhou Defang, Cheng Ziqiang
Abstract excerpt
Gyrovirus 3 (GyV3) has been identified in humans and other hosts, suggesting its cross-species pathogenicity, which poses an increased public health risk. In the current study, we established chicken and mouse models of GyV3 infection. We found that GyV3 induced persistent infections, characterized by viremia, aplastic anemia, immunosuppression, and systematic lymphocytic inflammation, in both species. Kinetic...
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