Article
Mesenteric Lymph Node Transplantation in Mice to Study Immune Responses of the Gastrointestinal Tract.
Frontiers in immunology - 1 Jan 2021
Shaikh Haroon, Vargas Juan Gamboa, Mokhtari Zeinab, Jarick Katja J, Ulbrich Maria, Mosca Josefina Peña, Viera Estibaliz Arellano, Graf Caroline, Le Duc-Dung, Heinze Katrin G, Büttner-Herold Maike, Rosenwald Andreas, Pezoldt Joern, Huehn Jochen, Beilhack Andreas
Abstract excerpt
Mesenteric lymph nodes (mLNs) are sentinel sites of enteral immunosurveillance and immune homeostasis. Immune cells from the gastrointestinal tract (GIT) are constantly recruited to the mLNs in steady-state and under inflammatory conditions resulting in the induction of tolerance and immune cells activation, respectively. Surgical dissection and transplantation of lymph nodes (LN) is a technique that has...
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