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New insights into mitophagy and stem cells

11 Aug 2021

Abstract excerpt

Mitophagy is a specific autophagic phenomenon in which damaged or redundant mitochondria are selectively cleared by autophagic lysosomes. A decrease in mitophagy can accelerate the aging process. Mitophagy is related to health and longevity and is the key to protecting stem cells from metabolic stress damage. Mitophagy decreases the metabolic level of stem cells by clearing active mitochondria, so mitophagy is...

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PMID: 34380561
DOI: 10.1186/s13287-021-02520-5

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