Article
Interpreting and integrating genomic tests results in clinical cancer care: Overview and practical guidance.
CA: a cancer journal for clinicians - 1 Jan 2000
Casolino Raffaella, Beer Philip A, Chakravarty Debyani, Davis Melissa B, Malapelle Umberto, Mazzarella Luca, Normanno Nicola, Pauli Chantal, Subbiah Vivek, Turnbull Clare, Westphalen C Benedikt, Biankin Andrew V
Abstract excerpt
The last decade has seen rapid progress in the use of genomic tests, including gene panels, whole-exome sequencing, and whole-genome sequencing, in research and clinical cancer care. These advances have created expansive opportunities to characterize the molecular attributes of cancer, revealing a subset of cancer-associated aberrations called driver mutations. The identification of these driver mutations can...
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