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Article

Untangling huge literature to disinter genetic underpinnings of Alzheimer's Disease: A systematic review and meta-analysis.

Ageing research reviews - 1 Nov 2021

G N S Hema Sree, Marise V Lakshmi Prasanna, Satish Kshreeraja S, Yergolkar Abhijna Vithal, Krishnamurthy Mamatha, Ganesan Rajalekshmi Saraswathy, Radhika K, Burri Raghunadha R

Abstract excerpt

Drug discovery for Alzheimer's Disease (AD) is channeled towards unravelling key disease specific drug targets/genes to predict promising therapeutic candidates. Though enormous literature on AD genetics is available, there exists dearth in data pertinent to drug targets and crucial pathological pathways intertwined in disease progression. Further, the research findings revealing genetic associations failed to...

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PMID: 34371203
DOI: 10.1016/j.arr.2021.101421

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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