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Article

Comparative analysis of the autism‑related variants between different autistic children in a family pedigree.

Molecular medicine reports - 1 Oct 2021

Shen Luxi, Li Panyuan, Zheng Tianjin, Luo Meichen, Zhang Shao, Huang Yuting, Hu Yongwu, Li Hongzhi

Abstract excerpt

The present study aimed to provide evidence for the genetic heterogeneity of familial autism spectrum disorder (ASD), which might help to improve our understanding of the complex polygenic basis of this disease. Whole‑exome sequencing (WES) was performed on two autistic children in a family pedigree, and reasonable conditions were set for preliminarily screening variant annotations. Sanger sequencing was used to...

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Identifiers

PMID: 34368859
DOI: 10.3892/mmr.2021.12336
PMCID: PMC8365409

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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