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Whole-genome sequencing identifies novel genes for autism in Chinese trios.

Science China. Life sciences - 1 Nov 2024

Chang Suhua, Liu Jia Jia, Zhao Yilu, Pang Tao, Zheng Xiangyu, Song Zhirui, Zhang Anyi, Gao Xuping, Luo Lingxue, Guo Yanqing, Liu Jing, Yang Li, Lu Lin

Abstract excerpt

Autism spectrum disorder (ASD) is a neurodevelopmental disorder with high genetic heritability but heterogeneity. Fully understanding its genetics requires whole-genome sequencing (WGS), but the ASD studies utilizing WGS data in Chinese population are limited. In this study, we present a WGS study for 334 individuals, including 112 ASD patients and their non-ASD parents. We identified 146 de novo variants in...

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PMID: 39126614
DOI: 10.1007/s11427-023-2564-8

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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