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Sc-compReg enables the comparison of gene regulatory networks between conditions using single-cell data

6 Aug 2021

Abstract excerpt

The comparison of gene regulatory networks between diseased versus healthy individuals or between two different treatments is an important scientific problem. Here, we propose sc-compReg as a method for the comparative analysis of gene expression regulatory networks between two conditions using single cell gene expression (scRNA-seq) and single cell chromatin accessibility data (scATAC-seq). Our software,...

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PMID: 34362918
DOI: 10.1038/s41467-021-25089-2

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