Hairy Cell Leukemia, Version 2.2018, NCCN Clinical Practice Guidelines in Oncology.

doi:10.6004/jnccn.2017.0165

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Article

Hairy Cell Leukemia, Version 2.2018, NCCN Clinical Practice Guidelines in Oncology.

Journal of the National Comprehensive Cancer Network : JNCCN - 1 Nov 2017

Wierda William G, Byrd John C, Abramson Jeremy S, Bhat Seema, Bociek Greg, Brander Danielle, Brown Jennifer, Chanan-Khan Asher, Coutre Steve E, Davis Randall S, Fletcher Christopher D, Hill Brian, Kahl Brad S, Kamdar Manali, Kaplan Lawrence D, Khan Nadia, Kipps Thomas J, Lancet Jeffrey, Ma Shuo, Malek Sami, Mosse Claudio, Shadman Mazyar, Siddiqi Tanya, Stephens Deborah, Wagner Nina, Zelenetz Andrew D, Dwyer Mary A, Sundar Hema

Abstract excerpt

Hairy cell leukemia (HCL) is a rare type of indolent B-cell leukemia, characterized by symptoms of fatigue and weakness, organomegaly, pancytopenia, and recurrent opportunistic infections. Classic HCL should be considered a distinct clinical entity separate from HCLvariant (HCLv), which is associated with a more aggressive disease course and may not respond to standard HCL therapies. Somatic hypermutation in the...

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PMID: 29118233
DOI: 10.6004/jnccn.2017.0165

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