Article
A Causal Web between Chronotype and Metabolic Health Traits.
Genes - 1 Jul 2021
Williams John A, Russ Dominic, Bravo-Merodio Laura, Cardoso Victor Roth, Pendleton Samantha C, Aziz Furqan, Acharjee Animesh, Gkoutos Georgios V
Abstract excerpt
Observational and experimental evidence has linked chronotype to both psychological and cardiometabolic traits. Recent Mendelian randomization (MR) studies have investigated direct links between chronotype and several of these traits, often in isolation of outside potential mediating or moderating traits. We mined the EpiGraphDB MR database for calculated chronotype-trait associations (p-value < 5 × 10-8). We...
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