Article
Alternative Lengthening of Telomeres Phenotype Predicts Progression Risk in Noninsulinomas in a Chinese Cohort.
Neuroendocrinology - 1 Jan 2022
Ban Xinchao, Mo Shengwei, Lu Zhaohui, Jia Congwei, Shao Huilin, Yan Jie, Chang Xiaoyan, Mao Xinxin, Wu Yan, Zhang Yue, Fan Xiaojie, Yu Shuangni, Chen Jie
Abstract excerpt
INTRODUCTION: Recent studies have suggested that alternative lengthening of telomeres (ALT) is associated with metastasis and poor survival in pancreatic neuroendocrine tumors (PanNETs). This study evaluated whether this association is applicable to Chinese patients as well as the potential somatic mutations associated with ALT. METHODS: We assessed the prevalence of ALT by performing telomere-specific...
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