Article
The relationship of retinopathy of prematurity with brain-derivated neurotrophic factor, vascular endotelial growth factor-A, endothelial PAD domain protein 1 and nitric oxide synthase 3 gene polymorphisms.
Ophthalmic genetics - 1 Dec 2021
Ilguy Serdar, Cilingir Oguz, Bilgec Mustafa Deger, Ozalp Onur, Erzurumluoglu Gokalp Ebru, Arslan Serap, Tekin Neslihan, Aydemir Ozge, Erol Nazmiye, Colak Ertugrul, Gursoy Huseyin
Abstract excerpt
BACKGROUND: In addition to risk factors such as low birth weight and uncontrolled oxygen therapy, genetic predisposition is also thought to play a role in the development of retinopathy of prematurity (ROP). In our study, we aimed to analyze single-nucleotide polymorphisms (SNPs) in VEGFA, EPAS1, BDNF and NOS3 genes in infants who develop ROP. MATERIALS AND METHODS: Seventy-five mild-moderate and 73 severe ROP...
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