Article
Genetic association of single nucleotide polymorphisms of FZD4 and BDNF genes with retinopathy of prematurity.
Ophthalmic genetics - 1 Jun 2018
Lasabova Zora, Stanclova Andrea, Grendar Marian, Mikolajcikova Silvia, Calkovska Andrea, Lenhartova Nina, Ziak Peter, Matasova Katarina, Caprnda Martin, Kruzliak Peter, Zibolen Mirko
Abstract excerpt
BACKGROUND: Retinopathy of prematurity (ROP) is a multifactorial disease occurring in preterm neonates, caused by incorrect development of retinal blood vessels. It has been suggested that, in addition to gestational age, weight, and oxygen supplementation, genetic factors can play a role in the pathogenesis of ROP. METHODS: In the present prospective study, 97 neonates were enrolled based on the gestational age...
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