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Article

Genetic polymorphisms of vascular endothelial growth factor and risk for retinopathy of prematurity in South of Iran.

Molecular biology reports - 1 Jul 2013

Kalmeh Zahra Asadi, Azarpira Negar, Mosallaei Mahnaz, Hosseini Hamid, Malekpour Zahra

Abstract excerpt

Retinopathy of prematurity (ROP) is a multifactorial disease, that cause visual impairment in premature children. The exact pathogenesis and etiology of ROP is unknown and genetic susceptibility is considered as risk factor. Vascular endothelial growth factor (VEGF) plays a major role in retinal neovascularization and subsequently retinal detachment. VEGF polymorphism is associated with proliferative ROP in some...

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PMID: 23644986
DOI: 10.1007/s11033-013-2554-y

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