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Article

Disparate regulation of IMD signaling drives sex differences in infection pathology in Drosophila melanogaster.

Proceedings of the National Academy of Sciences of the United States of America - 10 Aug 2021

Vincent Crystal M, Dionne Marc S

Abstract excerpt

Male and female animals exhibit differences in infection outcomes. One possible source of sexually dimorphic immunity is the sex-specific costs of immune activity or pathology, but little is known about the independent effects of immune- versus microbe-induced pathology and whether these may differ for the sexes. Here, by measuring metabolic and physiological outputs in Drosophila melanogaster with wild-type and...

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Identifiers

PMID: 34341118
DOI: 10.1073/pnas.2026554118
PMCID: PMC8364183

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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