Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genome-Wide MicroRNA Analysis of Peripheral Blood Mononuclear Cells Reveals Elevated miR-142-3p Expression as a Potential Biomarker for Secondary Syphilis.

BioMed research international - 1 Jan 2021

Yang Zhusheng, Yang Xiumin, Gan Zhaoyan, Yuan Liang, Liu Wei, Si Chaozeng

Abstract excerpt

BACKGROUND: Treponema pallidum subspecies pallidum (T. pallidum) infection induces significant immune responses, resulting in tissue damage. Gene expression plays an essential role in regulating the progression of syphilis infection. However, little is known about the regulatory role of microRNAs (miRNAs) in the immune response to T. pallidum infection. Here, we analyze the differential expression of miRNAs in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biomarkers
Share to Gene Ontology

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genome, Human

Share to Immunity

Share to Leukocytes, Mononuclear

Share to MicroRNAs

Share to Protein Interaction Maps

Share to Syphilis

Source

Open in PubMed Open full text

Identifiers

PMID: 34337017
DOI: 10.1155/2021/5520053
PMCID: PMC8317471

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genome-Wide MicroRNA Analysis of Peripheral Blood Mononuclear Cells Reveals Elevated miR-142-3p Expression as a Potential Biomarker for Secondary Syphilis.PMID 34337017Read ↗

MicroRNA expression profiling of peripheral blood mononuclear cells associated with syphilisSemantic proximity Read ↗

MicroRNA expression profiling of peripheral blood mononuclear cells associated with syphilisSemantic proximity Read ↗

Peripheral blood mononuclear cell microRNA profiles in syphilitic patients with serofast statusSemantic proximity Read ↗

Syphilis and the host: multi-omic analysis of host cellular responses to Treponema pallidum provides novel insight into syphilis pathogenesisSemantic proximity Read ↗

Biological Basis for SyphilisSemantic proximity Read ↗

Immunophenotypic variations in syphilis: insights from Mendelian randomization analysis.Semantic proximity Read ↗

Time-course Transcriptomics Reveals the Impact of <i>Treponema pallidum</i> on Microvascular Endothelial Cell Function and PhenotypeSemantic proximity Read ↗

The Arg753Gln Polymorphism of Toll-Like Receptor 2 Has a Lower Occurrence in Patients with Syphilis, Suggesting Its Protective Effect in Czech and Slovak Individuals.Semantic proximity Read ↗

Treponema pallidum inhibits CD4+ T-cell proliferation through METAP2: insights from Mendelian randomization analysisSemantic proximity Read ↗

Sensitive detection of Treponema pallidum DNA from the whole blood of patients with syphilis by the nested PCR assaySemantic proximity Read ↗

Insights into the mysterious genetic variation profile of <i>tprK</i> in <i>Treponema pallidum</i> under the development of natural human syphilis infectionSemantic proximity Read ↗

Molecular investigation of Treponema pallidum strains associated with ocular syphilis in the United States, 2016-2020.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.