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Mitophagy in Huntington's disease

28 Jul 2021

Abstract excerpt

Huntington's disease (HD), as well as Parkinson's disease and Alzheimer's disease, belong to a group of neurodegenerative diseases characterized by common features, such as the progressive loss of neurons and the presence of pathogenic forms of misfolded protein aggregates. A quality control system such as autophagy is crucial for the clearance of protein aggregates and dysfunctional organelles and thus essential...

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PMID: 34329735
DOI: 10.1016/j.neuint.2021.105147

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