Article
Two Novel Mutations Associated with Polymyxin-B Resistance in a Pandemic Lineage of Uropathogenic Escherichia coli of the Sequence Type 69.
Chemotherapy - 1 Jan 2021
Dos Santos Carla Adriana, Hernandes Rodrigo Tavanelli, Cunha Marcos Paulo Vieira, Nagamori Filipe Onishi, Gonçalves Claudia Regina, Sacchi Claudio Tavares, Tiba-Casas Monique Ribeiro, Camargo Carlos Henrique
Abstract excerpt
BACKGROUND: Uropathogenic Escherichia coli (UPEC) are frequent pathogens worldwide, impacting on the morbidity and economic costs associated with antimicrobial treatment. OBJECTIVES: We report two novel mutations associated with polymyxin-B resistance in an UPEC isolate collected in 2019. METHODS: Isolate was submitted to antimicrobial susceptibility testing including broth microdilution for polymyxin B. Whole...
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