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Article

Imipenem Resistance in Clostridium difficile Ribotype 017, Portugal.

Emerging infectious diseases - 1 Apr 2018

Isidro Joana, Santos Andrea, Nunes Alexandra, Borges Vítor, Silva Catarina, Vieira Luís, Mendes Aristides L, Serrano Mónica, Henriques Adriano O, Gomes João Paulo, Oleastro Mónica

Abstract excerpt

We describe imipenem-resistant and imipenem-susceptible clinical isolates of Clostridium difficile ribotype 017 in Portugal. All ribotype 017 isolates carried an extra penicillin-binding protein gene, pbp5, and the imipenem-resistant isolates had additional substitutions near the transpeptidase active sites of pbp1 and pbp3. These clones could disseminate and contribute to imipenem resistance.

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Identifiers

PMID: 29553322
DOI: 10.3201/eid2404.170095
PMCID: PMC5875251

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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