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Optimizing of a suitable protocol for isolating tissue‐derived extracellular vesicles and profiling small RNA patterns in hepatocellular carcinoma

22 Jul 2024

Abstract excerpt

BACKGROUND: Extracellular vesicles (EVs) facilitate cell-cell interactions in the tumour microenvironment. However, standard and efficient methods to isolate tumour tissue-derived EVs are lacking, and their biological functions remain elusive. METHODS: To determine the optimal method for isolating tissue-derived EVs, we compared the characterization and concentration of EVs obtained by three previously reported...

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PMID: 39037259
DOI: 10.1111/liv.16011

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