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Sexual dimorphism of monocyte transcriptome in individuals with chronic low-grade inflammation

28 Jul 2021

Abstract excerpt

Sexual dimorphism in the immune system is evidenced by a higher prevalence of autoimmune diseases in women and higher susceptibility to infectious diseases in men. However, the molecular basis of these sex-based differences is not fully understood. We have characterized the transcriptome profiles of peripheral blood monocytes from males and postmenopausal females with chronic low-grade inflammation. We identified...

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PMID: 34321081
DOI: 10.1186/s13293-021-00387-y

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