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Article

Functional and mutational analysis after radiation and cetuximab treatment on prostate carcinoma cell line DU145.

Radiation oncology (London, England) - 28 Jul 2021

Schneider Raik, Gademann Günther, Ochel Hans-Joachim, Neumann Karsten, Jandrig Burkhard, Hass Peter, Walke Mathias, Schostak Martin, Brunner Thomas, Christoph Frank

Abstract excerpt

BACKGROUND: Epidermal Growth Factor Receptor is often overexpressed in advanced prostate carcinoma. In-vitro-studies in prostate carcinoma cell line DU145 have demonstrated increased sensibility to radiation after cetuximab treatment, but clinical data are not sufficient to date. METHODS: We analyzed effects of radiation and cetuximab in DU145 and A431 using proliferation, colony-forming-unit- and...

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Identifiers

PMID: 34321039
DOI: 10.1186/s13014-021-01859-6
PMCID: PMC8317395

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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