Impact of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Variant-Associated Receptor Binding Domain (RBD) Mutations on the Susceptibility to Serum Antibodies Elicited by Coronavirus Disease 2019 (COVID-19) Infection or Vaccination.

doi:10.1093/cid/ciab656

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Impact of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Variant-Associated Receptor Binding Domain (RBD) Mutations on the Susceptibility to Serum Antibodies Elicited by Coronavirus Disease 2019 (COVID-19) Infection or Vaccination.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America - 3 May 2022

Chen Lin-Lei, Lu Lu, Choi Charlotte Yee-Ki, Cai Jian-Piao, Tsoi Hoi-Wah, Chu Allen Wing-Ho, Ip Jonathan Daniel, Chan Wan-Mui, Zhang Ricky Ruiqi, Zhang Xiaojuan, Tam Anthony Raymond, Lau Daphne Pui-Ling, To Wing-Kin, Que Tak-Lun, Yip Cyril Chik-Yan, Chan Kwok-Hung, Cheng Vincent Chi-Chung, Yuen Kwok-Yung, Hung Ivan Fan-Ngai, To Kelvin Kai-Wang

Abstract excerpt

BACKGROUND: Several severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) lineages with mutations at the spike protein receptor binding domain (RBD) have reduced susceptibility to antibody neutralization, and have been classified as variants of concern (VOCs) or variants of interest (VOIs). Here we systematically compared the neutralization susceptibility and RBD binding of different VOCs/VOIs, including...

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PMID: 34309648
DOI: 10.1093/cid/ciab656

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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