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Reduced sensitivity of infectious SARS-CoV-2 variant B.1.617.2 to monoclonal antibodies and sera from convalescent and vaccinated individuals

2021-05-27

Abstract excerpt

The SARS-CoV-2 B.1.617 lineage emerged in October 2020 in India 1–6 . It has since then become dominant in some indian regions and further spread to many countries. The lineage includes three main subtypes (B1.617.1, B.1617.2 and B.1.617.3), which harbour diverse Spike mutations in the N-terminal domain (NTD) and the receptor binding domain (RBD) which may increase their immune evasion potential. B.1.617.2 is bel...

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Literature Corpus work
81fe6d68-62e0-5029-afc9-10a6f2091a5b
DOI
10.1101/2021.05.26.445838
Open publication

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Reduced sensitivity of infectious SARS-CoV-2 variant B.1.617.2 to monoclonal antibodies and sera from convalescent and vaccinated individualsDOI 10.1101/2021.05.26.445838
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