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RBM15-mediated N6-methyladenosine modification affects COVID-19 severity by regulating the expression of multitarget genes

23 Jul 2021

Abstract excerpt

Severe coronavirus disease 2019 (COVID-19) is characterized by symptoms of lymphopenia and multiorgan damage, but the underlying mechanisms remain unclear. To explore the function of N6-methyladenosine (m6A) modifications in COVID-19, we performed microarray analyses to comprehensively characterize the m6A epitranscriptome. The results revealed distinct global m6A profiles in severe and mild COVID-19 patients....

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PMID: 34301919
DOI: 10.1038/s41419-021-04012-z

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