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Structural comparison of typical and atypical E2 pestivirus glycoproteins

3 Jan 2024

Abstract excerpt

Pestiviruses, within the family Flaviviridae, are economically important viruses of livestock. In recent years, new pestiviruses have been reported in domestic animals and non-cloven-hoofed animals. Among them, atypical porcine pestivirus (APPV) and Norway rat pestivirus (NRPV) have relatively little sequence conservation in their surface glycoprotein E2. Despite E2 being the main target for neutralizing...

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PMID: 38176409
DOI: 10.1016/j.str.2023.12.003

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