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Article

Hydroxychloroquine induces oxidative DNA damage and mutation in mammalian cells.

DNA repair - 1 Oct 2021

Besaratinia Ahmad, Caliri Andrew W, Tommasi Stella

Abstract excerpt

Since the early stages of the pandemic, hydroxychloroquine (HCQ), a widely used drug with good safety profile in clinic, has come to the forefront of research on drug repurposing for COVID-19 treatment/prevention. Despite the decades-long use of HCQ in the treatment of diseases, such as malaria and autoimmune disorders, the exact mechanisms of action of this drug are only beginning to be understood. To date, no...

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Identifiers

PMID: 34298488
DOI: 10.1016/j.dnarep.2021.103180
PMCID: PMC8435022

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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