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Article

An immunogenomic phenotype predicting behavioral treatment response: Toward precision psychiatry for mothers and children with trauma exposure.

Brain, behavior, and immunity - 1 Jan 2022

Aschbacher Kirstin, Cole Steve, Hagan Melissa, Rivera Luisa, Baccarella Alyssa, Wolkowitz Owen M, Lieberman Alicia F, Bush Nicole R

Abstract excerpt

Inflammatory pathways predict antidepressant treatment non-response among individuals with major depression; yet, this phenomenon may have broader transdiagnostic and transtherapeutic relevance. Among trauma-exposed mothers (Mage = 32 years) and their young children (Mage = 4 years), we tested whether genomic and proteomic biomarkers of pro-inflammatory imbalance prospectively predicted treatment response (PTSD...

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Identifiers

PMID: 34298096
DOI: 10.1016/j.bbi.2021.07.012

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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