Article
Adversity in early life and pregnancy are immunologically distinct from total life adversity: macrophage-associated phenotypes in women exposed to interpersonal violence.
Translational psychiatry - 20 Jul 2021
Aschbacher Kirstin, Hagan Melissa, Steine Iris M, Rivera Luisa, Cole Steve, Baccarella Alyssa, Epel Elissa S, Lieberman Alicia, Bush Nicole R
Abstract excerpt
Early childhood and pregnancy are two sensitive periods of heightened immune plasticity, when exposure to adversity may disproportionately increase health risks. However, we need deeper phenotyping to disentangle the impact of adversity during sensitive periods from that across the total lifespan. This study examined whether retrospective reports of adversity during childhood or pregnancy were associated with...
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