Article
Mast cell activation syndrome: is anaphylaxis part of the phenotype? A systematic review.
Current opinion in allergy and clinical immunology - 1 Oct 2021
Sabato Vito, Michel Moïse, Blank Ulrich, Ebo Didier G, Vitte Joana
Abstract excerpt
PURPOSE OF REVIEW: Mast cell activation syndrome (MCAS) and anaphylaxis are the result of a spontaneous or triggered pathological degranulation of mast cells (MCs) and might have as substrate normal or pathological MCs (increased burden, aberrant MCs or both). RECENT FINDINGS: This review summarizes the most recent evidence on immunoglobulin E (IgE)-mediated and non IgE-mediated mechanisms underlying MC...
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