Article
Hymenoptera Anaphylaxis and C-kit Mutations: An Unexpected Association.
Current allergy and asthma reports - 1 Aug 2015
Bonadonna Patrizia, Bonifacio Massimiliano, Lombardo Carla, Zanotti Roberta
Abstract excerpt
Clinical manifestations of mastocytosis in adults comprise signs and symptoms linked to mast cell (MC) activation, including anaphylaxis. Depending on MC burden, adults can be diagnosed with systemic mastocytosis, when the WHO criteria are fulfilled, or with other clonal MC disorders, characterized by MC mediator symptoms and demonstration of activating KIT mutations and/or expression of CD25 on MCs. There is a...
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