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An association study in the Taiwan Biobank elicits three novel candidates for cognitive aging in old adults: NCAM1, TTC12 and ZBTB20.

Aging - 20 Jul 2021

Lin Eugene, Kuo Po-Hsiu, Lin Wan-Yu, Liu Yu-Li, Yang Albert C, Tsai Shih-Jen

Abstract excerpt

The dopamine receptor-related loci have been suggested to be associated with cognitive functions and neurodegenerative diseases. It is unknown whether genetic variants such as single nucleotide polymorphisms (SNPs) in the dopamine receptor-related loci could contribute to cognitive aging independently as well as by virtue of complicated interplays in the elder population. To assess whether SNPs in the dopamine...

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PMID: 34285142
DOI: 10.18632/aging.203321
PMCID: PMC8351692

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