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Article

Identification of LIPH as an unfavorable biomarkers correlated with immune suppression or evasion in pancreatic cancer based on RNA-seq.

Cancer immunology, immunotherapy : CII - 1 Mar 2022

Zhuang Hongkai, Chen Xinming, Wang Ying, Huang Shanzhou, Chen Bo, Zhang Chuanzhao, Hou Baohua

Abstract excerpt

BACKGROUND: It is widely considered that pancreatic cancer (PC) is an immunosuppressive cancer. Immune-based therapies remain promising therapeutic strategies for PC. Overexpression of lipase H (LIPH) was reported to be related to immunity in cattle and has also been demonstrated to promote tumor progression in several tumors, but its role in pancreatic carcinogenesis remains unclear. Study on LIPH in PC might...

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Source

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Identifiers

PMID: 34279685
DOI: 10.1007/s00262-021-03019-x
PMCID: PMC10992541

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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