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Article

Why do people seek out polygenic risk scores for complex disorders, and how do they understand and react to results?

European journal of human genetics : EJHG - 1 Jan 2022

Peck Larissa, Borle Kennedy, Folkersen Lasse, Austin Jehannine

Abstract excerpt

We sought to explore individuals' motivations for using their direct-to-consumer genetic testing data to generate polygenic risk scores (PRSs) using a not-for-profit third-party tool, and to assess understanding of, and reaction to their results. Using a cross-sectional design, users of Impute.me who had already accessed PRS results were invited to complete an online questionnaire asking about demographics,...

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Identifiers

PMID: 34276054
DOI: 10.1038/s41431-021-00929-3
PMCID: PMC8738734

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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