Article
Data integration uncovers the metabolic bases of phenotypic variation in yeast.
PLoS computational biology - 1 Jul 2021
Petrizzelli Marianyela Sabina, de Vienne Dominique, Nidelet Thibault, Noûs Camille, Dillmann Christine
Abstract excerpt
The relationship between different levels of integration is a key feature for understanding the genotype-phenotype map. Here, we describe a novel method of integrated data analysis that incorporates protein abundance data into constraint-based modeling to elucidate the biological mechanisms under...
Topics
- Biological Variation, Population
- Computational Biology
- Databases, Genetic
- Fermentation
- Glycolysis
- Phenotype
- Saccharomyces cerevisiae