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Article

Integrative genome-wide analyses reveal the transcriptional aberrations in Japanese esophageal squamous cell carcinoma.

Cancer science - 1 Oct 2021

Takemoto Akira, Tanimoto Kousuke, Mori Seiichi, Inoue Jun, Fujiwara Naoto, Noda Tetsuo, Inazawa Johji

Abstract excerpt

Esophageal squamous cell carcinoma (ESCC) is a malignant disease. At present, the genomic profiles of ESCC are known to a considerable extent, and DNA methylation and gene expression profiles have been mainly used for the classification of ESCC subtypes, but integrative genomic, transcriptomic, and epigenomic analyses remain insufficient. Therefore, we performed integrative analyses using whole-exome sequencing,...

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Identifiers

PMID: 34263978
DOI: 10.1111/cas.15063
PMCID: PMC8486213

Genes

NFE2L2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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