Article
RORC gene polymorphism is associated with acute kidney injury following cardiac surgery.
Acta anaesthesiologica Scandinavica - 1 Nov 2021
Gholamipoor Zeynab, Rahimzadeh Mahsa, Montazerghaem Hossein, Naderi Nadereh
Abstract excerpt
BACKGROUND: Acute kidney injury (AKI) is a common complication of cardiopulmonary bypass (CPB), associated with increased mortality in surgical patients. It is well-proven that Th17 and its hallmark cytokine, IL-17, contribute to AKI development. Since the RAR-related orphan receptor C (RORC) gene is a master regulator of the Th17 differentiation, we aimed to evaluate the association between its polymorphisms,...
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