Article
Identification of Targetable Gene Fusions and Structural Rearrangements to Foster Precision Medicine inKRASWild-Type Pancreatic Cancer
11 Jan 2021
Abstract excerpt
PURPOSE It has recently been described that alternative oncogenic drivers may be found in KRAS wild-type ( KRASWT) pancreatic cancers. This study aimed to determine the incidence of targetable gene fusions present in KRASWTpancreatic adenocarcinoma and response to targeted therapy. METHODS One hundred consecutive patients with pancreatic adenocarcinoma who underwent targeted next-generation sequencing using DNA...
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